E-AB-60967
HSD17B10 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60967
- Zusätzliche Namen:
- 17b-HSD10,ABAD,CAMR,DUPXp11.22,ERAB,HADH2,HCD2,HSD10MD,HSD17B10,MHBD,MRPP2,MRX17,MRX31,MRXS10,SCHAD,SDR5C1
- Anwendung:
- IHC, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human HSD17B10 (NP_004484.1).
- Uniprot:
- Q99714
- Synonyme:
- 17-beta-hydroxysteroid dehydrogenase 10;17b-HSD10;2-methyl-3-hydroxybutyryl-CoA dehydrogenase;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;3-hydroxyacyl-CoA dehydrogenase type II;3-hydroxyacyl-CoA dehydrogenase type-2;AB-binding alcohol dehydrogenase;ABAD;amyloid-beta peptide binding alcohol dehydrogenase;CAMR;DUPXp11.22;endoplasmic reticulum-associated amyloid beta-peptide-binding protein;ERAB;HADH2;HCD2;HSD10MD;MHBD;mitochondrial ribonuclease P protein 2;mitochondrial RNase P subunit 2;MRPP2;MRX17;MRX31;MRXS10;SCHAD;SDR5C1;Short chain dehydrogenase/reductase family 5C member 1;short chain L-3-hydroxyacyl-CoA dehydrogenase type 2;short chain type dehydrogenase/reductase XH98G2;Short-chain type dehydrogenase/reductase XH98G2;Type II HADH
- Weitere Details:
- This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
- Versandbedingungen:
- Blue Ice