E-AB-60743
TBK1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60743
- Zusätzliche Namen:
- FTDALS4,NAK,T2K,TBK1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TBK1 (NP_037386.1).
- Uniprot:
- Q9UHD2
- Synonyme:
- FTDALS4;IIAE8;NAK;NF-kappa-B-activating kinase;NF-kB-activating kinase;serine/threonine-protein kinase TBK1;T2K;TANK-binding kinase 1
- Weitere Details:
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
- Versandbedingungen:
- Blue Ice