E-AB-60583
CDKN1C Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60583
- Zusätzliche Namen:
- BWCR,BWS,CDKN1C,KIP2,WBS,p57,p57Kip2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human CDKN1C (NP_000067.1).
- Uniprot:
- P49918
- Synonyme:
- BWCR;BWS;cyclin-dependent kinase inhibitor 1C;cyclin-dependent kinase inhibitor 1C (p57, Kip2);cyclin-dependent kinase inhibitor p57;KIP2;p57;p57Kip2;WBS
- Weitere Details:
- This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice