RFC1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-60380
Zusätzliche Namen:: A1,MHCBFB,PO-GA,RECC1,RFC,RFC1,RFC140
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human RFC1 (NP_001191676.1).
Uniprot:: P35251
Synonyme:: A1;A1 140 kDa subunit;activator 1 140 kDa subunit;activator 1 large subunit;activator 1 subunit 1;CANVAS;DNA-binding protein PO-GA;MHC binding factor, beta;MHCBFB;PO-GA;RECC1;replication factor C (activator 1) 1, 145kDa;replication factor C 140 kDa subunit;replication factor C large subunit;replication factor C subunit 1;replication factor C1;RF-C 140 kDa subunit;RFC;RFC140
Weitere Details:: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.