E-AB-60352
Factor IX / F9 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60352
- Zusätzliche Namen:
- F9,F9 p22,F9p22,FIX,HEMB,P19,PTC,THPH8
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human Factor IX / F9 (NP_000124.1).
- Uniprot:
- P00740
- Synonyme:
- Christmas factor;coagulation factor IX;F9 p22;factor 9;factor IX F9;FIX;HEMB;P19;plasma thromboplastic component;plasma thromboplastin component;PTC;THPH8
- Weitere Details:
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
- Versandbedingungen:
- Blue Ice