E-AB-60308
CBS Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60308
- Zusätzliche Namen:
- CBS,HIP4
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CBS (NP_000062.1).
- Uniprot:
- P35520
- Synonyme:
- beta-thionase;CBS;CBSL;cystathionine beta-synthase;Cystathionine beta-synthase-like protein;HIP4;methylcysteine synthase;serine sulfhydrase
- Weitere Details:
- The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
- Versandbedingungen:
- Blue Ice