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E-AB-60286

TYR Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-60286
Zusätzliche Namen:
ATN,CMM8,OCA1,OCA1A,OCAIA,SHEP3,TYR
Anwendung:
IHC, WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TYR
Uniprot:
P14679
Synonyme:
ATN;CMM8;LB24-AB;monophenol monooxygenase;OCA1;OCA1A;OCAIA;oculocutaneous albinism IA;SHEP3;SK29-AB;tumor rejection antigen AB;tyrosinase
Weitere Details:
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Versandbedingungen:
Blue Ice