E-AB-60279
Ataxin 3 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60279
- Zusätzliche Namen:
- AT3,ATX3,ATXN3,Ataxin 3,JOS,MJD,MJD1,SCA3,ataxin-3
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human Ataxin 3 (NP_004984.2).
- Uniprot:
- P54252
- Synonyme:
- AT3;ataxin-3;ATX3;JOS;josephin;Machado-Joseph disease protein 1;MJD;MJD1;olivopontocerebellar ataxia 3;SCA3;spinocerebellar ataxia type 3 protein
- Weitere Details:
- Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Versandbedingungen:
- Blue Ice