E-AB-60220
ACTN1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-60220
- Zusätzliche Namen:
- ACTN1,BDPLT15
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ACTN1 (NP_001123477.1).
- Uniprot:
- P12814
- Synonyme:
- actinin 1 smooth muscle;Alpha-actinin cytoskeletal isoform;alpha-actinin-1;BDPLT15;epididymis secretory sperm binding protein;F-actin cross-linking protein;non-muscle alpha-actinin-1
- Weitere Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice