TNNT2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-60197
Zusätzliche Namen:: CMD1D,CMH2,CMPD2,LVNC6,RCM3,TNNT2,TnTC,cTnT,troponin T2
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TNNT2 (NP_001001431.1).
Uniprot:: P45379
Synonyme:: Cardiac muscle troponin T;cardiomyopathy, dilated 1D (autosomal dominant);cardiomyopathy, hypertrophic 2;CMD1D;CMH2;CMPD2;cTnT;LVNC6;RCM3;TnTC;troponin T type 2 (cardiac);troponin T, cardiac muscle;truncated cardiac troponin T
Weitere Details:: The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.