E-AB-60027
BMP2 Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-60027
- Zusätzliche Namen:
- BDA2,BMP2,BMP2A
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BMP2 (NP_001191.1).
- Uniprot:
- P12643
- Synonyme:
- BDA2;BMP2A;bone morphogenetic protein 2;bone morphogenetic protein 2A;SSFSC;SSFSC1
- Weitere Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
- Versandbedingungen:
- Blue Ice