E-AB-60009
BAK1 Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-60009
- Zusätzliche Namen:
- BAK,BAK-LIKE,BAK1,BCL2L7
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human BAK1 (NP_001179.1).
- Uniprot:
- Q16611
- Synonyme:
- apoptosis regulator BAK;BAK;BAK-LIKE;bcl-2 homologous antagonist/killer;bcl-2-like protein 7;bcl2-L-7;BCL2-like 7 protein;BCL2L7;CDN1;pro-apoptotic protein BAK
- Weitere Details:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
- Versandbedingungen:
- Blue Ice