E-AB-53586
ATN1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-53586
- Zusätzliche Namen:
- ATN1,Atrophin1,B37,D12S755E,DRPLA,Dentatorubral-pallidoluysian atrophy protein,HRS,NOD
- Anwendung:
- IHC
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ATN1
- Uniprot:
- P54259
- Synonyme:
- atrophin-1;B37;CHEDDA;D12S755E;dentatorubral-pallidoluysian atrophy protein;DRPLA;HRS;NOD
- Weitere Details:
- Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.ATN1 (Atrophin 1) is a Protein Coding gene. Diseases associated with ATN1 include Dentatorubro-Pallidoluysian Atrophy and Spinocerebellar Ataxia 1. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is RERE.
- Versandbedingungen:
- Blue Ice