E-AB-53542
YBX1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-53542
- Zusätzliche Namen:
- BP 8,CBF-A,CCAAT binding transcription factor I subunit A,CCAAT-binding transcription factor I subunit A,CSDA2,CSDB,DBPB,DNA binding protein B,DNA-binding protein B,EFI-A,Enhancer factor I subunit A,MDR NF1,MGC104858,MGC110976,MGC117250,NSEP 1,NSEP1,Nucle
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human YBX1
- Uniprot:
- P67809
- Synonyme:
- BP-8;CBF-A;CCAAT-binding transcription factor I subunit A;CSDA2;CSDB;DBPB;DNA-binding protein B;EFI-A;enhancer factor I subunit A;major histocompatibility complex, class II, Y box-binding protein I;MDR-NF1;NSEP-1;NSEP1;nuclease-sensitive element-binding protein 1;Y-box transcription factor;Y-box-binding protein 1;YB-1;YB1
- Weitere Details:
- This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
- Versandbedingungen:
- Blue Ice