E-AB-53303
CLK2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-53303
- Zusätzliche Namen:
- CDC like kinase 2,CDC-like kinase 2,CLK 2,CLK kinase,CLK2,Clk2 Scamp3,Dual specificity protein kinase CLK2,Tu52,hCLK 2,hCLK2
- Anwendung:
- IHC
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CLK2
- Uniprot:
- P49760
- Synonyme:
- CDC-like kinase 2;CLK kinase;dual specificity protein kinase CLK2
- Weitere Details:
- This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates.Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing.Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein.Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation.There is a pseudogene for this gene on chromosome 7.Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice