ZBTB10 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-53220
Zusätzliche Namen:: FLJ12752,OTTHUMP00000207119,RINZF,RINZFC,ZBT10,ZBTB10,Zinc finger and BTB domain containing protein 10,Zinc finger and BTB domain-containing protein 10,Zinc finger protein RIN ZF
Anwendung:: WB
Konzentration:: 0.5 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human ZBTB10
Uniprot:: Q96DT7
Synonyme:: RINZF;zinc finger and BTB domain-containing protein 10;zinc finger protein RIN ZF;zinc finger protein RINZF
Weitere Details:: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.