E-AB-53145
FBXO8 Polyclonal Antibody

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£106.20
War £118.00
- SKU:
- E-AB-53145
- Zusätzliche Namen:
- DC10,F box only protein 8,F box protein 8,F box protein Fbx8,F box/SEC7 protein FBS ,F-box only protein 8,F-box/SEC7 protein FBS,FBS,FBX8,FBXO 8,Fbxo8
- Anwendung:
- IHC
- Konzentration:
- 0.72 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human FBXO8
- Uniprot:
- Q9NRD0
- Synonyme:
- DC10;F-box only protein 8;F-box protein Fbx8;F-box/SEC7 protein FBS;FBS;FBX8
- Weitere Details:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
- Versandbedingungen:
- Blue Ice