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E-AB-53145

FBXO8 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-53145
Zusätzliche Namen:
DC10,F box only protein 8,F box protein 8,F box protein Fbx8,F box/SEC7 protein FBS ,F-box only protein 8,F-box/SEC7 protein FBS,FBS,FBX8,FBXO 8,Fbxo8
Anwendung:
IHC
Konzentration:
0.72 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human FBXO8
Uniprot:
Q9NRD0
Synonyme:
DC10;F-box only protein 8;F-box protein Fbx8;F-box/SEC7 protein FBS;FBS;FBX8
Weitere Details:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Versandbedingungen:
Blue Ice