E-AB-53126
TNNT1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-53126
- Zusätzliche Namen:
- slow skeletal type,ANM,MGC104241,NEM5,Skeletal,Slow ,Slow skeletal muscle troponin T,TNNT1,TNT,TnTs,Tnnt1,Troponin T,Troponin T slow skeletal muscle,Troponin T type 1 (skeletal slow),Troponin T1,sTnT,slow skeletal muscle,troponin T1 skeletal slow
- Anwendung:
- IHC, WB
- Konzentration:
- 0.66 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human TNNT1
- Uniprot:
- P13805
- Synonyme:
- ANM;NEM5;slow skeletal muscle troponin T;STNT;TNT;TNTS;troponin T type 1 (skeletal, slow);troponin T, slow skeletal muscle;troponin-T1, skeletal, slow
- Weitere Details:
- This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice