E-AB-53060
GCSH Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-53060
- Zusätzliche Namen:
- GCE,GCSH,Glycine cleavage system H protein,Glycine cleavage system H protein mitochondrial,Glycine cleavage system protein H,Glycine cleavage system protein H (aminomethyl carrier),Lipoic acid containing protein,Mitochondrial glycine cl,mitochondrial
- Anwendung:
- IHC
- Konzentration:
- 1.08 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human GCSH
- Uniprot:
- P23434
- Synonyme:
- GCE;glycine cleavage system H protein, mitochondrial;glycine cleavage system protein H (aminomethyl carrier);lipoic acid-containing protein;mitochondrial glycine cleavage system H-protein;NKH
- Weitere Details:
- Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
- Versandbedingungen:
- Blue Ice