E-AB-52915
ELF3 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52915
- Zusätzliche Namen:
- E74 like factor 3,E74 like factor 3 ETS domain transcription factor serine box epithelial specific,E74 like factor 3 ets domain transcription factor,E74 like factor 3 ets domain transcription factor epithelial specific,E74-like factor 3,ELF3,Elf3,Epitheli
- Anwendung:
- IHC
- Konzentration:
- 1.02 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ELF3
- Uniprot:
- P78545
- Synonyme:
- E74-like factor 3;E74-like factor 3 (ets domain transcription factor, epithelial-specific );E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific);E74-like factor 3 (ets domain transcription factor);epithelial-restricted with serine box;epithelium-restricted Ets protein ESX;epithelium-specific Ets transcription factor 1;EPR-1;ERT;ESE-1;ESX;ets domain transcription factor, serine box (epithelial-specific);ETS-related transcription factor Elf-3
- Weitere Details:
- Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
- Versandbedingungen:
- Blue Ice