E-AB-52886
DUSP7 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52886
- Zusätzliche Namen:
- DUS7,Dual specificity phosphatase 7,Dual specificity protein phosphatase 7,Dual specificity protein phosphatase PYST2,Dusp7,JSP1,Jnk Stimulatory Phosphatase 1,MAP kinase phosphatase X,MKPX,PYST2
- Anwendung:
- IHC
- Konzentration:
- 0.66 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human DUSP7
- Uniprot:
- Q16829
- Synonyme:
- dual specificity protein phosphatase 7;dual specificity protein phosphatase PYST2;MKPX;PYST2
- Weitere Details:
- Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).
- Versandbedingungen:
- Blue Ice