E-AB-52736
KRR1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52736
- Zusätzliche Namen:
- homolog (yeast), small subunit (SSU) processome component,HIV 1 Rev binding protein 2,HIV-1 Rev-binding protein 2,HRB2,KRR1,KRR1 small subunit processome component homolog,RIP 1 ,Rev interacting protein 1,Rev-interacting protein 1,Rip-1
- Anwendung:
- IHC
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human KRR1
- Uniprot:
- Q13601
- Synonyme:
- HIV-1 rev binding protein 2;HIV-1 Rev-binding protein 2;HRB2;KRR-R motif-containing protein 1;KRR1 small subunit processome component homolog;KRR1, small subunit (SSU) processome component, homolog;Rev interacting protein;rev-interacting protein 1;RIP-1
- Weitere Details:
- The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
- Versandbedingungen:
- Blue Ice