E-AB-52548
CLCN7 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52548
- Zusätzliche Namen:
- CLC 7,CLCN7,Chloride channel protein 7,ClC-7,ClC7,FLJ26686,FLJ39644,FLJ46423,H(+)/Cl(-) exchange transporter 7,OPTA2,OPTB4
- Anwendung:
- IHC
- Konzentration:
- 1.56 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human CLCN7
- Uniprot:
- P51798
- Synonyme:
- chloride channel 7 alpha subunit;chloride channel protein 7;chloride channel, voltage-sensitive 7;CLC-7;CLC7;H(+)/Cl(-) exchange transporter 7;HOD;OPTA2;OPTB4;PPP1R63;protein phosphatase 1, regulatory subunit 63
- Weitere Details:
- The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
- Versandbedingungen:
- Blue Ice