E-AB-52505
C4BPB Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52505
- Zusätzliche Namen:
- C4BP,C4BPB,C4b binding protein beta chain,C4b-binding protein beta chain,Complement component 4 binding protein beta,Complement component 4 binding protein beta chain,Complement component 4-binding protein beta,OTTHUMP00000034288,OTTHUMP00000034289
- Anwendung:
- IHC
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human C4BPB
- Uniprot:
- P20851
- Synonyme:
- C4b-binding protein beta chain;C4BP
- Weitere Details:
- This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids.A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway.C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster.Alternative splicing gives rise to multiple transcript variants.
- Versandbedingungen:
- Blue Ice