COA7 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-52496
Zusätzliche Namen:: C1orf163,Chromosome 1 open reading frame 163,FLJ12439,Hcp beta lactamase like protein C1orf163,Hypothetical protein LOC65260,RESA1,Sel1 repeat containing 1,beta-lactamase hcp-like protein,sel1 repeat-containing protein 1
Anwendung:: IHC, WB
Konzentration:: 0.9 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Full length fusion protein
Uniprot:: Q96BR5
Synonyme:: beta-lactamase hcp-like protein;C1orf163;cytochrome c oxidase assembly factor 7;cytochrome c oxidase assembly factor 7 (putative);epididymis secretory sperm binding protein;hcp beta-lactamase-like protein C1orf163;RESA1;respiratory chain assembly 1;respiratory chain assembly factor 1;SCAN3;Sel1 repeat containing 1;sel1 repeat-containing protein 1;SELRC1
Weitere Details:: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. COA7 (cytochrome c oxidase assembly factor 7), also known as RESA1, SELRC1 or C1orf163, is a 231 amino acid mitochondrial protein that belongs to the hcp beta-lactamase family. Consisting of five Sel1-like repeats, COA7 may be associated with respiratory chain assembly. COA7 is encoded by a gene located on human chromosome 1p32.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene, which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.

Versandbedingungen:: Blue Ice