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E-AB-52440

UMPS Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-52440
Zusätzliche Namen:
ODC,OMPdecase,OPRT,OPRTase,Orotate phosphoribosyl transferase and orotidine 5' decarboxylase,Orotate phosphoribosyltransferase,Orotate phosphoribosyltransferase phosphoribosyltransferase,Orotidine 5' phosphate decarboxylase,Orotidine 5''-phosphate decarbo
Anwendung:
IHC, WB
Konzentration:
0.7 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human UMPS
Uniprot:
P11172
Synonyme:
OMPdecase;OPRT;OPRTase;orotate phosphoribosyltransferase;orotidine 5'-phosphate decarboxylase;UMP synthase;uridine 5'-monophosphate synthase
Weitere Details:
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Versandbedingungen:
Blue Ice