E-AB-52354
METTL7A Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52354
- Zusätzliche Namen:
- AAM B,AAMB,DKFZP586A0522,MET7A,METTL 7A,METTL7A,METTL7A methlytransferase like 7A,Methyltransferase like 7A,Methyltransferase-like protein 7A,Protein AAM-B,Protein AAMB
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human METTL7A
- Uniprot:
- Q9H8H3
- Synonyme:
- AAM-B;AAMB;methyltransferase-like protein 7A;protein AAM-B
- Weitere Details:
- METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
- Versandbedingungen:
- Blue Ice