LRRC19 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-52280
Zusätzliche Namen:: FLJ21302,LRC19,LRRC 19,LRRC19,Leucine rich repeat containing 19,Leucine-rich repeat-containing protein 19,leucine rich repeat containing protein 19
Anwendung:: IHC, WB
Konzentration:: 1.1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human LRRC19
Uniprot:: Q9H756
Synonyme:: leucine-rich repeat-containing protein 19
Weitere Details:: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.