SCP2 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-52211
Zusätzliche Namen:: DKFZp686C12188,DKFZp686D11188,NLTP,NSL TP,NSL-TP,Non-specific lipid-transfer protein,Nonspecific lipid transfer protein,OTTHUMP00000010488,OTTHUMP000002317,OTTHUMP00000231766,OTTHUMP00000231767,OTTHUMP00000231768,OTTHUMP00000231769,OTTHUMP00000231770
Anwendung:: IHC, WB
Konzentration:: 0.6 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human SCP2
Uniprot:: P22307
Synonyme:: acetyl-CoA C-myristoyltransferase;epididymis secretory sperm binding protein;NLTP;non-specific lipid-transfer protein;NSL-TP;propanoyl-CoA C-acyltransferase;SCOX;SCP-2;SCP-2/3-oxoacyl-CoA thiolase;SCP-2/thiolase;SCP-CHI;SCP-X;SCPX;sterol carrier protein 2;sterol carrier protein X;straight-chain acyl-CoA oxidase
Weitere Details:: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Versandbedingungen:: Blue Ice