E-AB-52202
PTPRN Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52202
- Zusätzliche Namen:
- CA 512,FLJ16131,IA 2,IA 2/PTP,IA2,IA2/PTP,ICA 3,ICA 512,ICA3,ICA512,Islet cell antigen 2,Islet cell antigen 512,Islet cell autoantigen 3,Protein tyrosine phosphatase like N,Protein tyrosine phosphatase like N precursor,Protein tyrosine phosphatase recepto
- Anwendung:
- IHC
- Konzentration:
- 0.96 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human PTPRN
- Uniprot:
- Q16849
- Synonyme:
- IA-2;IA-2/PTP;IA2;ICA 512;ICA512;insulinoma-associated tyrosine-phosphatase-like protein;islet cell antigen 2;islet cell antigen 512;islet cell autoantigen 3;protein tyrosine phosphatase-like N;PTP IA-2;R-PTP-N;receptor-type tyrosine-protein phosphatase-like N
- Weitere Details:
- IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
- Versandbedingungen:
- Blue Ice