E-AB-52133
AAK1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-52133
- Zusätzliche Namen:
- AAK 1,AAK1,AP2 associated kinase 1,AP2 associated protein kinase 1,AP2-associated protein kinase 1,Aak1,Adaptor associated kinase 1,Adaptor-associated kinase 1,DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,M,MGC138170
- Anwendung:
- WB
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human AAK1
- Uniprot:
- Q2M2I8
- Synonyme:
- adaptor-associated kinase 1;AP2-associated protein kinase 1
- Weitere Details:
- Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
- Versandbedingungen:
- Blue Ice