E-AB-40655
Lgals3 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- E-AB-40655
- Zusätzliche Namen:
- 35 kDa lectin, CBP 35, GALBP, Gal-3, Galactose-specific lectin 3, Galectin-3, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, MAC2, Mac-2 antigen,LGALS3
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Rat Lgals3 protein expressed by E.coli
- Uniprot:
- P08699
- Synonyme:
- 35 kDa lectin;AGE-R3;carbohydrate-binding protein 35;CBP 35;CBP30;epsilon BP;gal-3;galactose-specific lectin 3;galectin-3;IgE binding protein;igE-binding protein;L-34;laminin-binding protein;lectin galactoside-binding soluble 3 protein;lectin L-29;lectin, galactose binding, soluble 3;lectin, galactoside-binding, soluble, 3;mac-2 antigen
- Weitere Details:
- Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
- Versandbedingungen:
- Blue Ice