E-AB-40489
PCNA Polyclonal Antibody
Größe
£87.30
War £97.00
- SKU:
- E-AB-40489
- Zusätzliche Namen:
- Cyclin, DNA polymerase delta auxiliary protein, HGCN8729, MGC8367, Mutagen-sensitive 209 protein, PCNA, PCNAR, Pcna/cyclin, Polymerase delta accessory protein, Proliferating cell nuclear antigen, cb16, etID36690.10, fa28e03, fb36g03,ATLD2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Synthetic peptide of Human Proliferating cell nuclear antigen
- Uniprot:
- P12004
- Synonyme:
- ATLD2;cyclin;DNA polymerase delta auxiliary protein;proliferating cell nuclear antigen
- Weitere Details:
- Proliferating Cell Nuclear Antigen,commonly known as PCNA,is a protein that acts as a processivity factor for DNA polymerase D Delta in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase,but not apurinic-apyrimidinic (AP) endonuclease,APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution, the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
- Versandbedingungen:
- Blue Ice