E-AB-40477
NPM1 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- E-AB-40477
- Zusätzliche Namen:
- MGC104254, NO38, NPM, NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin, Nucleophosmin (nucleolar phosphoprotein B23 numatrin), Nucleophosmin/nucleoplasmin family member 1, Num, nucleophosmin nucleoplasmin family member 1,B23
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse Nucleophosmin protein
- Uniprot:
- Q61937
- Synonyme:
- B23;NO;NO38;Npm;nucleolar phosphoprotein B23;nucleolar protein NO38;nucleophosmin;numatrin
- Weitere Details:
- Nucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective,multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates,dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
- Versandbedingungen:
- Blue Ice