E-AB-40231
MCM7 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- E-AB-40231
- Zusätzliche Namen:
- S. cerevisiae, formerly, homolog of,CDABP0042,CDC 47,CDC47,CDC47 homolog,Cdc47,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM2,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Mcm7,Minichromosome Maintaine
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human DNA replication licensing factor MCM7 protien
- Uniprot:
- P33993
- Synonyme:
- CDC47;CDC47 homolog;DNA replication licensing factor MCM7;homolog of S. cerevisiae Cdc47;MCM2;minichromosome maintenance deficient 7;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104;protein phosphatase 1, regulatory subunit 104
- Weitere Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Versandbedingungen:
- Blue Ice