E-AB-40070
AB Beta40 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- E-AB-40070
- Zusätzliche Namen:
- A4,A4 amyloid protein,AAA,ABETA,ABPP,AD1,AICD-50,AICD-57,AICD-59,AID(50),AID(57),AID(59),Alzheimer disease amyloid protein,Amyloid beta (A4) precursor protein,Amyloid beta A4 protein,Amyloid beta protein,Amyloid intracellul,Amyloid intracellular domain 50
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse Beta-amyloid 40 protein
- Uniprot:
- P12023
- Synonyme:
- A;Abe;Abeta;Abpp;Adap;Ag;alzheimer disease amyloid A4 protein homolog;amyloid beta A4 protein;amyloid precursor protein;amyloid-beta A4 protein;amyloid-beta precursor protein;amyloidogenic glycoprotein;appican;bet;beta-amyloid precursor protein;betaApp;C;Cvap;E030013M08Rik;protease nexin II
- Weitere Details:
- AB Beta derives from APP via proteolytic cleavage by proteases called A Alpha-, B Beta- and G Gamma-secretase. The A Alpha-secretase cleavage precludes the formation of AB Beta, while the B Beta- and G Gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
- Versandbedingungen:
- Blue Ice