E-AB-40063
FAS Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- E-AB-40063
- Zusätzliche Namen:
- ALPS 1A,ALPS1A,APO 1,APO 1 cell surface antigen,APO1,APO1 cell surface antigen,APT 1,APT1,Apo 1 antigen,Apo-1 antigen,Apo1 antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,CD 95,CD 95 antigen,CD95
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant human Tumor necrosis factor receptor superfamily member 6 protein
- Uniprot:
- P25445
- Synonyme:
- ALPS1A;APO-1;Apo-1 antigen;APO-1 cell surface antigen;apoptosis antigen 1;apoptosis signaling receptor FAS;apoptosis-mediating surface antigen FAS;APT1;CD95;CD95 antigen;Fas (TNF receptor superfamily, member 6);Fas AMA;FAS1;FASLG receptor;FASTM;mutant tumor necrosis receptor superfamily member 6;TNF receptor superfamily member 6;TNFRSF6;tumor necrosis factor receptor superfamily member 6;tumor necrosis factor receptor superfamily, member 6
- Weitere Details:
- Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.
- Versandbedingungen:
- Blue Ice