SMAD2 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-32916
Zusätzliche Namen:: Drosophila,HsMAD2,JV18,JV18-1,JV181,MAD,MAD Related Protein 2,MAD homolog 2,MADH2,MADR2,MGC22139,MGC34440,Mad-related protein 2,Mother against DPP homolog 2,Mothers against decapentaplegic,Mothers against decapentaplegic homolog 2,hMAD-2,homolog of
Anwendung:: IHC, WB, IHC-P
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:: Synthesized peptide derived from human Smad2 around the non-phosphorylation site of Ser250.
Uniprot:: Q15796
Synonyme:: hMAD-2;hSMAD2;JV18;JV18-1;MAD homolog 2;Mad-related protein 2;MADH2;MADR2;mother against DPP homolog 2;mothers against decapentaplegic homolog 2;Sma- and Mad-related protein 2;SMAD family member 2;SMAD, mothers against DPP homolog 2
Weitere Details:: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.