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E-AB-32025

MFN2 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-32025
Zusätzliche Namen:
CMT2A,CMT2A2,CPRP 1,CPRP1,EC 3.6.5.-,Fzo,HSG,Hypertension related protein 1,KIAA0214,MARF,MFN 2,MFN2,Mfn2,Mitochondrial assembly regulatory factor,Mitofusin-2,Mitofusin2,Transmembrane GTPase MFN2,hyperplasia suppressor gene
Anwendung:
IHC, WB, IHC-P
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthesized peptide derived from the Internal region of human Mfn2.
Uniprot:
O95140
Synonyme:
CMT2A;CMT2A2;CMT2A2A;CMT2A2B;CPRP1;HMSN6A;HSG;hyperplasia suppressor;MARF;mitochondrial assembly regulatory factor;mitofusin-2;transmembrane GTPase MFN2
Weitere Details:
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Versandbedingungen:
Blue Ice