E-AB-31433
FLNA Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-31433
- Zusätzliche Namen:
- ABP 280,ABP-280,APBX,Actin-binding protein 280,Alpha filamin,Alpha-filamin,CSBS,CVD1,Endothelial actin binding protein,Endothelial actin-binding protein,FLN,FLN-A,FLN1,FLNA,FMD,Filamin 1,Filamin A,Filamin A alpha,Filamin-1,Filamin-A,MNS,NHBP,Non musc
- Anwendung:
- IHC, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human Filamin 1 around the non-phosphorylation site of Ser2152.
- Uniprot:
- P21333
- Synonyme:
- ABP-280;ABPX;actin binding protein 280;Actin-binding protein 280;alpha-filamin;CSBS;CVD1;endothelial actin-binding protein;epididymis secretory sperm binding protein;FGS2;filamin A, alpha;filamin-1;filamin-A;FLN;FLN-A;FLN1;FMD;MNS;NHBP;non-muscle filamin;OPD;OPD1;OPD2;XLVD;XMVD
- Weitere Details:
- The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice