E-AB-31261
E-Cadherin Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-31261
- Zusätzliche Namen:
- Arc 1,CADH1,CAM 120/80,CD 324,CD324,CD324 antigen,CDHE,Cadherin 1,Cadherin1,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin,cadherin 1 type 1 E-cadherin,cdh1,epithelial calcium dependant adhesion protein
- Anwendung:
- IHC, WB, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human E-cadherin
- Uniprot:
- P12830
- Synonyme:
- Arc-1;BCDS1;cadherin 1, E-cadherin (epithelial);cadherin 1, type 1, E-cadherin (epithelial);cadherin-1;calcium-dependent adhesion protein, epithelial;CAM 120/80;CD324;CDHE;cell-CAM 120/80;E-cadherin 1;ECAD;epididymis secretory sperm binding protein;epithelial cadherin;LCAM;UVO;uvomorulin
- Weitere Details:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
- Versandbedingungen:
- Blue Ice