PYCARD Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-30582
Zusätzliche Namen:: ASC,Apoptosis associated speck like protein containing a CARD,Apoptosis-associated speck-like protein containing a CARD,CARD 5,CARD5,Caspase recruitment domain containing protein 5,Caspase recruitment domain protein 5,Caspase recruitment domain-contai
Anwendung:: IHC, WB, IHC-P, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:: Synthesized peptide derived from the N-terminal region of human ASC
Uniprot:: Q9ULZ3
Synonyme:: apoptosis-associated speck-like protein containing a CARD;ASC;CARD5;caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;target of methylation-induced silencing 1;TMS;TMS-1;TMS1
Weitere Details:: Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.