E-AB-30003
Cleaved-CASP3 p12 (D175) Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-30003
- Zusätzliche Namen:
- A830040C14Rik,Apopain,CASP-3,CASP3,CC3,CPP-32,CPP32,CPP32B,Casp3a,Caspase 3,Caspase-3 subunit p12,Cysteine p,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,apoptosis-related cysteine protease a
- Anwendung:
- IHC, WB, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from the Internal region of human Caspase-3 p12
- Uniprot:
- P42574
- Synonyme:
- apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP-32;CPP32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1
- Weitere Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- Versandbedingungen:
- Blue Ice