E-AB-22175
NFKBIB Monoclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-22175
- Zusätzliche Namen:
- I kappa B beta,I-kappa-B-beta,IKB beta,IKBB,IkB-B,IkB-beta,IkBbeta,IkappaBbeta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Nfkbib,TR interacting protein 9,TR-intera,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9
- Anwendung:
- IHC, IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant Protein
- Klon:
- 3E4
- Uniprot:
- Q15653
- Synonyme:
- I-kappa-B-beta;ikappaBbeta;ikB-B;ikB-beta;IKBB;NF-kappa-B inhibitor beta;NF-kappa-BIB;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta;thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9;TRIP9
- Weitere Details:
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
- Versandbedingungen:
- Blue Ice