Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Monoclonal

E-AB-22169

TBP Monoclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-22169
Zusätzliche Namen:
GTF2D,GTF2D1,HDL4,SCA17,TATA binding factor,TATA box binding protein,TATA box factor,TATA sequence binding protein,TATA sequence-binding protein,TATA-binding factor,TATA-box factor,TATA-box-binding protein,TBP,TFIID,Transcription initiation factor TFI
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Mouse
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Recombinant Protein
Klon:
4H2
Uniprot:
P20226
Synonyme:
GTF2D;GTF2D1;HDL4;SCA17;TATA sequence-binding protein;TATA-binding factor;TATA-box binding protein N-terminal domain;TATA-box factor;TATA-box-binding protein;TFIID;transcription initiation factor TFIID TBP subunit
Weitere Details:
This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Versandbedingungen:
Blue Ice