E-AB-22010
AMACR Monoclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-22010
- Zusätzliche Namen:
- 2 methylacyl CoA racemase,2-methylacyl-CoA racemase,AMACR,AMACRD,Alpha methylacyl CoA racemase,Alpha-methylacyl-CoA racemase,Amacr,CBAS4,EC 5.1.99.4,Macr1,RACE,RM
- Anwendung:
- IHC, WB, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthetic Peptide
- Klon:
- 1F1
- Uniprot:
- Q9UHK6
- Synonyme:
- 2-methylacyl-CoA racemase;alpha-methylacyl-CoA racemase;AMACRD;CBAS4;P504S;RACE;RM
- Weitere Details:
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
- Versandbedingungen:
- Blue Ice