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E-AB-21282

Phospho-CXCR4 (Ser339) Polyclonal Antibody

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£106.20

War £118.00

SKU:
E-AB-21282
Zusätzliche Namen:
C-X-C chemokine receptor type 4,CD184,CD184 antigen,CXC-R4,CXCR-4,CXCR4,Chemokine (C X C motif) receptor 4,Chemokine CXC Motif Receptor 4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP 3,LAP3,LCR1,LESTR,Leuk,Leukocyte derived seven transmembrane domain receptor
Anwendung:
IHC, WB, IHC-P, IF
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339
Uniprot:
P61073
Synonyme:
C-X-C chemokine receptor type 4;CD184;CD184 antigen;chemokine (C-X-C motif) receptor 4;D2S201E;FB22;fusin;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;leukocyte-derived seven transmembrane domain receptor;lipopolysaccharide-associated protein 3;LPS-associated protein 3;neuropeptide Y receptor Y3;neuropeptide Y3 receptor;NPY3R;NPYR;NPYRL;NPYY3R;SDF-1 receptor;seven transmembrane helix receptor;seven-transmembrane-segment receptor, spleen;stromal cell-derived factor 1 receptor;WHIM;WHIMS;WHIMS1
Weitere Details:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1.The protein has 7 transmembrane regions and is located on the cell surface.It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells.Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Versandbedingungen:
Blue Ice