E-AB-21179
Phospho-PAK1 (Thr212) Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-21179
- Zusätzliche Namen:
- ADRB2,Alpha PAK,Alpha-PAK,MGC130000,MGC130001,p21 activated kinase 1,p21 protein (Cdc42/Rac) activated kinase 1,p21-activated kinase 1,p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related),p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog,p65 PAK,yeast)
- Anwendung:
- IHC, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human PAKA Alpha around the phosphorylation site of Thr212
- Uniprot:
- Q13153
- Synonyme:
- alpha-PAK;IDDMSSD;p21 protein (Cdc42/Rac)-activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast);p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related);p65-PAK;PAKalpha;serine/threonine-protein kinase PAK 1;STE20 homolog, yeast
- Weitere Details:
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
- Versandbedingungen:
- Blue Ice