E-AB-19877
FNIP2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19877
- Zusätzliche Namen:
- FNIP1-like protein,FNIP2,FNIPL,Fnip2,Folliculin-interacting protein 2,KIAA1450,MAPO1,O6-methylguanine-induced apoptosis 1 protein,OTTHUMP00000221326
- Anwendung:
- WB
- Konzentration:
- 1.14 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human FNIP2
- Uniprot:
- Q9P278
- Synonyme:
- FNIP1-like protein;FNIPL;folliculin-interacting protein 2;MAPO1;O6-methylguanine-induced apoptosis 1 protein
- Weitere Details:
- This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin.
- Versandbedingungen:
- Blue Ice