E-AB-19841
FAM111B Polyclonal Antibody
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£106.20
War £118.00
- SKU:
- E-AB-19841
- Zusätzliche Namen:
- CANP ,Cancer associated nucleoprotein,Protein FAM111B
- Anwendung:
- IHC
- Konzentration:
- 1.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human FAM111B
- Uniprot:
- Q6SJ93
- Synonyme:
- cancer-associated nucleoprotein;CANP;family with sequence similarity 111 member B;POIKTMP;serine protease FAM111B
- Weitere Details:
- This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.
- Versandbedingungen:
- Blue Ice